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KMID : 1231220100010020096
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Journal of the Korean Society for Research on Nicotine and Tobacco
2010 Volume.1 No. 2 p.96 ~ p.106
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Smoking and Smoking Cessation in the Patients with Major Psychiatric Disorders
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Joe Keun-Ho
Lee Kye-Seong
Kim Dai-Jin
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Abstract
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Mentally ill patients presenting psychiatric symptoms or substance abusers have been reported to have serious smoking problems. In general, patients with psychiatric disorders have a higher prevalence rate of nicotine dependence and a higher daily cigarette consumption. Some studies reported that smokers with psychiatric disorders were more likely to fail to quit smoking than healthy people. Smoking prevalence in Korean male adults is above 40%, and it is not decreasing despite the nationwide health promotion services through public health centers. More individualized approaches will be required to decrease smoking prevalence. Identifying mental illnesses in smokers and adopting the most appropriate therapeutic tools should be considered. Quite a lot of clinical data have supported that nicotine replacement therapy and bupropion SR are effective for smoking cessation and safe among the mentally ill patients. However, varenicline should be used with a caution for the schizophrenics because of its action as partial dopamine agonist. Also, treating depressed smokers with varenicline is also cautious because of possible suicidality. In the meantime, the use of varenicline for the alcoholic smokers could be beneficial for treating alcoholism and nicotine dependence.
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KEYWORD
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Schizophrenia, Depressive disorder, Alcoholics, Smoking cessation
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